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Lithium and Prozac – the Newest Cocktail

For a couple of months now I’ve been taking 900mg of Lithium and 40mg of Prozac each day. I stopped taking the Seroquel about 4 months back, but I might have to get back on that because my sleep problems are back. It really helped me to get a solid nights rest, but I wanted to stop taking it as soon as was practical. Now I realize that like my other medications, I might need to take Seroquel daily forever as well.

The Lithium/Prozac combo works pretty well for me, but it took a couple of weeks before I got used to the Lithium. I had stomach problems a lot, but that was the only noticeable side effect. I had to take it with food in the beginning, but now I can take it on an empty stomach if I need to and it’s no problem. I like the Lithium because it’s processed by the kidneys, not the liver, like so many of the other anti-depressant/mood stabilizer drugs out there – my liver needs a break!
I do still have some days where I feel like a non-person for reason at all. I don’t have as many manic episodes now, which is what the Lithium is primarily supposed to control. I am certainly better off than with no meds, which you’d think by now I’d have that irrefutable fact tattooed on my brain. But, like the super-genius I think I am, I always try to push my luck at some point and stop taking some or all of my chemicals.
I like this current cocktail, though, and I am going to stick with it. I did have to start out on a lower dose of Lithium at first, and then after blood tests, upgrade to the 900mg a day. There’s a very tight range of effectiveness of the drug in your blood stream – I was under at first, and now I think it’s right on target. Anyway, I just thought I’d put that down on paper. Cheers.

2 Responses to “Lithium and Prozac – the Newest Cocktail”

  1. Arthur says:

    I know this is an old post and sorry for commenting but reading this helped a bit put me at ease on these meds. My doctor just put me on Prozac and lithium but for panic disorder with agoraphobia and depressive disorder. Was taking zoloft and it wasn’t working

    I was freaking out about these new meds and reading about the interactions and was about to leave my pharmacy right now….I think frequently how things will go bad to worse and just hate all this sometimes.

    But thanks and I hope you are really better nowadays…take care

    • ddadmin says:

      Hi Arthur – you don’t have to apologize for commenting, I am glad you did actually. I found that Prozac is a pretty mild (in terms of side effects particularly) antidepressant and also helped me with some of the anxiety and OCD symptoms as well. I would regularly get panic attacks before getting on a consistent drug combination like this. It’s interesting because now that I am just on Depakote (and the occasional Hydroxyzine before bed) I feel pretty well-balanced and a lot less anxious than I used to be. So as you can see, I am still working through what works for me long-term, but I’m glad to hear you’re trying something and even making the effort can be difficult sometimes. It’s never fun to have to go through the process of new medicines and combinations, so good for you. I always try to remember that there are so many different options out there that something will likely work. As long as you don’t give up trying.

      Take care, and let me know how the Prozac and lithium works out for you. I wish you the best!

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